Advancing from Research to Development
ResearchUncategorised
March 7, 2022

The Progression From Research to Development

Learn how we work with the EPA and state regulatory agencies to address solid waste management challenges.
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Consulting For Pharma
Uncategorised
June 11, 2020

Mitochondrial Uncoupling: If You Want to Live Longer, Look to the Skies

Over the years an enormous amount of both scientific and pseudo-scientific speculation has been aimed at explaining prevailing trends in the lifespan of animals,and how we might apply those lessons to humans. Since clear, observable trends exist with respect to various groups of animals and lifespan, if we can understand the underlying processes behind those trends, we might be able to extend and maximize our own lifespans.  The most obvious trend is body size versus lifespan, which is robust and repeatable, yet has some outliers that offer tantalizing grounds for speculation. Figure 1 shows the trend between size and lifespan.  The trend lines, both of which have significant scatter, clearly show two trends, with the data broken down to illustrate the difference between flying and non-flying species.  The striking difference between species who can and cannot fly will be immediately available to anyone who has ever kept a parrot – some species can reliably outlive their human owners. A number of…
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Uncategorised
June 4, 2020

Will Big Pharma Sabotage its’ Own Re-Shoring?

The need to reshore American products has been recognized on a federal level for many decades, with legislation such as the original Buy American Act, dated to 1933. The urgency has grown in recent years, with the burgeoning dependence of the United States on foreign medicines and medical equipment now constituting a huge strategic burden.  The issue has recently come to forefront because of  renewed distrust in supply chain stability thanks to Covid-19, however, and current legislation is upping the ante by including Big Pharma among the list of key players that need to be reformed. The imperative to return American products home is primarily being addressed through legislation offering incentives aimed at making American businesses more competitive, imposing tariffs on foreign goods and offering tax benefits for American manufacturers.  Although 28% of registered worldwide pharmaceutical API manufacturing sites are located within the US, according to government statistics when we consider the sourcing of raw materials, various estimates suggest that…
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Uncategorised
April 24, 2020

Thanks for the Plague, California!

Because if hiding dead bodies isn’t a conspiracy, we don’t know what is.The bubonic plague (and its’ siblings, the septicemic and pneumonic plagues) is alive and well in the Western United States.  In fact, in the most plague-stricken region in the United States (Northern New Mexico) several cases pop up every year.  Even with modern antibiotics, nearly 1 in 6 plague patients will die – which is still better than no treatment at all, since some forms are 99% fatal if untreated. Thanks to horizontal gene transfers and other mechanisms, soon antibiotics may not even help: one recently isolated strain of the plague was found to be resistant to eight antibiotics, including all of the three primary treatments for plague.  Even more disturbing, a Nevada woman who eventually died was treated for a bacterial infection in early 2017 that was resistant to every antibiotic available in the United States.  Yersinia pestis typically hides out in long-term environmental reservoirs, which may provide more…
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BlogUncategorised
February 12, 2020

E-Cigarettes Come Under Fire

  It has been nearly four weeks since Beverly Hills, CA, became the first US jurisdiction to categorically ban e-cigarette products, along with most other tobacco products.  (more…)
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BlogUncategorised
February 12, 2020

The Rising Tide of Preventable Diseases

  In the midst of the current measles outbreak in the United States, a great deal of controversy has arisen regarding the role of “anti-vaxxers” in perpetuating the spread of contagious diseases. (more…)
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Uncategorised
November 22, 2019

Toxoplasma Gondii: The Brain Hitchhiker

Toxoplasmosis is a widely known disease that results from infection with the Toxoplasma gondii parasite, one of the world's most common parasites. Infection usually occurs by eating undercooked contaminated meat, exposure from infected cat feces, or mother-to-child transmission during pregnancy.  Estimates suggest that about 1/3 of the entire human population of the Western world is harboring the parasite in the form of “benign cysts” concentrated mostly in the brain. The parasite can form cysts anywhere almost: hearts, lungs and eyeballs are common hiding places, but the brain is the preferred hangout for this organism.  If you are a cat lover, chances are high you are already infected, courtesy of your cat.  Cat brains are a natural repository for the adult protists, which reproduce inside our feline friends and spread from cat feces.  This is not to say that won’t infect any warm-blooded animal that they are capable of, but the only hosts truly necessary for their continued survival are felids, according to the CDC website. …
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Uncategorised
May 16, 2019

Anti-Cancer Gut Bacteria

The human microbiome is the subject of a burgeoning field of research.  The effect of gut microflora, and especially bacteria, has in the last few years been linked to anxiety, depression, gastrointestinal and autoimmune diseases, and numerous other disorders. (more…)
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Uncategorised
April 26, 2019

Greens Based Diet Slashes Risk of Heart Failure

Recent research conducted by Dr. Kyla Lara and colleagues, published in the Journal of the American College of Cardiology, examined the associations between five major diets and the risk of heart failure among people without any known history of heart disease. (more…)
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